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Esthesioneuroblastoma

Esthesioneuroblastoma

Esthetineuroblastoma presents with numerous chromosomal aberrations, deletions, and gains, but no consistent pattern. In one study, specific deletions of chromosome 11 and gains of chromosome 1p were associated with metastasis and poor prognosis [6]. Gains are more common than losses, and high-stage esthetic eurobratoma show more changes than low-stage tumors. Increases in 20q and 13q may be important for the progression of this neoplasm. These regions may harbor genes functionally related to esthesion eurobratoma. PTCH1, GL/1, and GL/2 were detected in 70%, 70%, and 65% of human esthesion euroblastoma specimens, respectively, implicating the SHH signaling pathway in the pathogenesis of this neoplasm. suggesting that it is possible.

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