Allied Academies

Cancer Metabolism

Cancer Metabolism

The rapid proliferation of liver cancer creates vulnerabilities in its energy production and cell aggregation processes that can be effectively exploited in new combination therapeutic strategies. Hepatocytes, the main type of primary liver cancer (HCC) alters its metabolism to make it vulnerable to disruption of the supply of the key molecule arginine. They found that this arginine vulnerability was present in all his HCC cancers, regardless of the specific genetic mutation that caused them.

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